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The Egyptian clinical practice guidelines for the diagnosis and management of knee osteoarthritis

Mohamed Mortada · Mohamed Hassan Abu-Zaid · Ahmed Abogamal · Ahmed Hatem Farhan Imam · Ahmed S. Hegab · Amr Fouad · Hala Lotfy Fayed · Hany Mohamed Aly · K. M. Emara · Mervat Eissa · Mohamed Ismail Abdelkareem · Naglaa Gadallah · Nahla Gaballah · Nouran Abaza · Osama Sayed Daifallah Mohamed · Rehab Ali Ibrahim · Sherif Eldaw · Waleed A. Hassan · Yasser El Miedany · Youmna A. Amer · Mona Hasab El Naby
10.1186/s43166-025-00325-5 388 Views 1 Citations
1
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388
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Abstract

Abstract

Background
Knee osteoarthritis (KOA) is a widespread, debilitating condition that drastically impacts the quality of life and healthcare systems globally. In Egypt, the burden of KOA is increasing due to an aging population, rising obesity rates, and lifestyle factors. Recognizing the urgent need for tailored recommendations, this article introduces the Egyptian Clinical Practice Guidelines for KOA diagnosis and management. These guidelines address Egypt's specific demographic, socioeconomic, and healthcare challenges.


Results
The guidelines provide a comprehensive framework for diagnosing KOA, affirming clinical evaluation supported by imaging and laboratory findings when necessary. They integrate global evidence-based practices with local expertise and resources to ensure relevance and applicability. The recommendations prioritize a multidisciplinary approach, emphasizing patient-centered care through lifestyle modifications, physical therapy, pharmacological interventions, and the appropriate use of intra-articular therapies. For advanced cases unresponsive to conservative measures, surgical options are outlined. Special attention is given to enhancing the accessibility and affordability of treatments in alignment with the constraints of the Egyptian healthcare system.


Conclusion
These guidelines aim to standardize KOA management, facilitate early detection, and improve patient outcomes across diverse healthcare settings. By offering clear, evidence-based recommendations, they serve as a critical tool for healthcare professionals, policymakers, and stakeholders, significantly reducing the burden of KOA in Egypt.

Cite this Article (APA)
Mohamed, M., Mohamed, H. A., Ahmed, A., Ahmed, H. F. I., Ahmed, S. H., Amr, F., Hala, L. F., Hany, M. A., K., M. E., Mervat, E., Mohamed, I. A., Naglaa, G., Nahla, G., Nouran, A., Osama, S. D. M., Rehab, A. I., Sherif, E., Waleed, A. H., Yasser, E. M., Youmna, A. A., Mona, H. E. N. (2025). The Egyptian clinical practice guidelines for the diagnosis and management of knee osteoarthritis. Egyptian Rheumatology and Rehabilitation. https://doi.org/10.1186/s43166-025-00325-5
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Published in
ISSN 2090-3235
Quartile Q3
AMS Score 76
Field Medicine & Health Sciences
Publisher Springer (Biomed Central Ltd.)
Country 🇪🇬 Egypt
View Journal Profile →
Authors
M
Mohamed Hassan Abu-Zaid
W
Waleed A. Hassan
Publication Details
Year 2025
Language English
Added 14 Aug 2026