MK8722 alleviates osteoarthritis by activating Sesn2 and transcriptionally upregulating BNIP3 to promote mitophagy and inhibit chondrocyte ferroptosis

Haochen Wang; Ze Zhao; Jianbang Su; Wenzheng Chen; Haoyan Shi; Tianqi Gao; Minghao Yu; Lunhao Bai; Peng Dong; Qian Zhang; Chao Ji; Jingyu Yang; Yang Liu; Yingliang Wei

doi:10.1016/j.jare.2025.09.060

Q1 2026

MK8722 alleviates osteoarthritis by activating Sesn2 and transcriptionally upregulating BNIP3 to promote mitophagy and inhibit chondrocyte ferroptosis

Haochen Wang · Ze Zhao · Jianbang Su · Wenzheng Chen · Haoyan Shi · Tianqi Gao · Minghao Yu · Lunhao Bai · Peng Dong · Qian Zhang · Chao Ji · Jingyu Yang · Yang Liu · Yingliang Wei

10.1016/j.jare.2025.09.060 386 Views 7 Citations

Citations

386

Views

Abstract not available for this publication.

Cite this Article (APA)

Haochen, W., Ze, Z., Jianbang, S., Wenzheng, C., Haoyan, S., Tianqi, G., Minghao, Y., Lunhao, B., Peng, D., Qian, Z., Chao, J., Jingyu, Y., Yang, L., Yingliang, W. (2026). MK8722 alleviates osteoarthritis by activating Sesn2 and transcriptionally upregulating BNIP3 to promote mitophagy and inhibit chondrocyte ferroptosis. Journal of Advanced Research. https://doi.org/10.1016/j.jare.2025.09.060