Activating Sigma1R by fluoxetine suppresses neuronal ferroptosis in epilepsy by inhibiting MDM2-mediated GPX4 ubiquitination

Yuxiang Li; Cong Wang; Mengying Huang; Yanmin Lyu; Jixiang Sun; Chunxiao Du; Meng Liang; Juanrui Chen; Jiawen Lu; Ge Li; Zhiding Wang; Suxia Wu; Gencheng Han

doi:10.1016/j.jare.2026.07.060

Q1 2026

Activating Sigma1R by fluoxetine suppresses neuronal ferroptosis in epilepsy by inhibiting MDM2-mediated GPX4 ubiquitination

Yuxiang Li · Cong Wang · Mengying Huang · Yanmin Lyu · Jixiang Sun · Chunxiao Du · Meng Liang · Juanrui Chen · Jiawen Lu · Ge Li · Zhiding Wang · Suxia Wu · Gencheng Han

10.1016/j.jare.2026.07.060 388 Views 0 Citations

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Cite this Article (APA)

Yuxiang, L., Cong, W., Mengying, H., Yanmin, L., Jixiang, S., Chunxiao, D., Meng, L., Juanrui, C., Jiawen, L., Ge, L., Zhiding, W., Suxia, W., Gencheng, H. (2026). Activating Sigma1R by fluoxetine suppresses neuronal ferroptosis in epilepsy by inhibiting MDM2-mediated GPX4 ubiquitination. Journal of Advanced Research. https://doi.org/10.1016/j.jare.2026.07.060