The use of medicinal plants for healing dates back to ancient times. Beta vulgaris is a medicinal plant found in Yemen. Objective: The current study aimed to screen the phytochemicals, and to determine the inhibition effect of B. vulgaris extracts on α-amylase and pancreatic lipase. Methods: B. vulgaris was extracted using different solvents (ethanol 96% ethanol 50% or water), and screened for the possible phytochemicals. Furthermore, the plants extracts were studied for the α-amylase and pancreatic lipase inhibition effects according to the protocol of Cobas Company. Results: The findings of phytochemical screening showed the presence of alkaloids, saponins, terpenoids and tannins. B. vulgaris extracts showed α-amylase inhibition activity (59.26-63.66%). In addition, B. vulgaris extracts showed inhibition effects (40.87-48.45%) on pancreatic lipase, while BV50 exhibited the highest inhibition effects on α-amylase and pancreatic lipase. Conclusion: B. vulgaris extracts showed potential α-amylase and pancreatic lipase inhibition effects in vitro, suggesting possible anti-hyperglycemic and anti-obesity properties. Further research is recommended to carry out in vivo study for the anti-hyperglycemic and anti-obesity effects, and to isolate and determine the active compounds responsible for these effects.
Cite this Article (APA)
Mohammed, A. A. S., Alaa, A. M., Abdulrahman, A. B., Ahmed, H. B., Balqees, A. B., Ibrahim, S. B., Abdulrahman, S. A., Ahmed, S. A., Anisa, J. A., Hamdan, A. B., Saleh, A. A. (2025). Phytochemical Screening, in vitro α-amylase and Pancreatic Lipase Inhibition Effects of Beta vulgaris Extracts. Yemeni Journal For Medical Sciences. https://doi.org/10.20428/yjms.v19i3.2764
