Percutaneous coronary intervention in unprotected left main coronary artery stenosis patients. A Retrospective Study from Palestine

Objective: The study aimed to assess the results of stenting in unprotected left main cor-onary artery disease (uLMCAD) at a tertiary hospital center. Methods: We assessed all pa-tients who received stenting for uLMCAD, including stable patients who underwent elective, urgent, or emergent procedures. Data were gathered by reviewing hospital records and coro-nary angiograms and calculating SYNTAX scores. Patient follow-up was conducted via clinic visits and phone calls. Results: Percutaneous coronary intervention (PCI) was performed on seventy patients with uLMCAD, all of whom had successful revascularization. During their hospital stay, only one patient (1.4%) died from a noncardiac cause and no patient experi-enced target lesion failure. After an average follow-up of 17.4 ± 12.36 months, four patients (5.7%) died, with three of the deaths being noncardiac. Eight patients (11.4%) also experi-enced major adverse cardiac events, and six (8.6%) required target vessel revascularization. The crush technique was associated with a lower rate of target lesion failure than the non-crush technique (0% vs. 14%, p=0.03). Furthermore, patients with one- to two-vessel disease had lower rates of target lesion failure than those with three-vessel disease (2.5% vs. 16.7%, p=0.048). Other variables, such as the Syntax score and the lesion site (distal and nondistal left main disease), did not appear to affect target lesion outcomes. Conclusions: In our cen-ter, the stenting procedure for uLMCAD resulted in favorable outcomes during hospitaliza-tion and at the long-term follow-up, comparable to the results of large clinical trials.