Detection of the serum levels of some immunological parameters in patients with HBV

Introduction:. The current study set out to ascertain the serum concentrations of two complement compounds (C3 and C4) and several significant cytokines (IL-1β, IL-12, and IL-17A) in individuals infected with HBV.
Methods:.Ninety patients in all were gathered from the Baquba Teaching Hospital, and every diagnosis was made using an ELISA kit. The levels of IL-1β, IL-12, and IL-17A in serum samples from both HBV patients and healthy control groups were measured using an ELISA kit. The patient group exhibited elevated levels of IL-1β, IL-12, and IL-17A in comparison to the control group. A single radial immunodiffusion plate was utilized to compare the patient's levels of C3 and C4 to those of the control group.
Results :.When compared to the control group, the IL-1β, IL-12, IL-17A  show high levels and the C3 and C4 levels in the patients' serum were lower.
Conclusions:. It has been discovered that measuring the levels of IL-1β, IL-12, IL-17A, C3, and C4 can be useful in determining the extent of liver cell damage and forecasting how long hepatitis will take to proceed.