Background: Spontaneous pathological rupture of the malarial spleen (SPRMS) is a rare but serious complication that has no known predictor in the medical literature. This study aims to report a systematic review of the search for a predictor for SPRMS and the recent changes in the management trends and outcomes of this problem.
Methods: A systematic review of 122 cases from January of 2000 through March of 2024 was conducted and linear regression was computed to search for predicting factors for SPRMS.
Results: Plasmodium vivax (P. vivax) was the most common cause of SPRMS among local citizens, while Plasmodium falciparum (P. Falciparum) was predominant among infected travelers. Fifty patients underwent splenectomy. Despite being a confounding factor in logistic regression, blood pressure could be the sole predictor of SPRMS.
Conclusion: Recent management trends have shown a tendency toward conservative treatment to preserve splenic immunological functions. To our knowledge, this is the first report on a predicting factor for SPRMS. This is important for early diagnosis and health management, as securing patient safety is a cornerstone of clinical governance in emergency settings.
Cite this Article (APA)
MohamedAhmed, M. I., Eltahir, A. E., Mohammed, M. I., Mohamed, H. A., Hassan, B. A., Mohammed, H., Atif, A. M. S., Suliman, S. F. (2025). Predictor of Spontaneous Rupture of Malarial Spleen: A Systematic Review and Meta-analysis. Sudan Journal of Medical Sciences. https://doi.org/10.18502/sjms.v20i1.16587
